idf diabetes atlas 2021 citation

The IDF Diabetes Atlas also introduces readers to the pathophysiology of diabetes, its classification and its diagnostic criteria. Amongst SU-treated patients, gliclazide users were 9% more likely to have an HbA1c<7% and had a 19% lower risk of self-reported hypoglycaemia (after adjustment for covariables such as countries/areas and year of recruitment) (Fig. Preprint. Adjusting the Use of Glucose-Lowering Agents in the Real-World Clinical Management of People with Type2 Diabetes: A Narrative Review. During this time, the publication has established itself as the most cited and trusted source on the global impact of diabetes and an indispensable tool for diabetes advocacy. https://doi.org/10.1007/s00125-011-2404-1. With each new . Methods Citations. Araki E, Goto A, Kondo T, et al. IDF Diabetes Atlas 10th Edition 2021. . This field is for validation purposes and should be left unchanged. Of the gliclazide users, two-thirds had received two OGLDs, with 78% receiving concomitant metformin. It is also estimated that over 6.7 million people aged 20-79 will die from diabetes-related causes in 2021. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. Diabetes Care. https://doi.org/10.1056/NEJMoa0802987. Diabetes Research and Clinical PracticeHong Sun; Pouya Saeedi; Suvi Karuranga; Moritz Pinkepank; Katherine Ogurtsova; Bruce B. Duncan; Carol . https://doi.org/10.2337/dci17-0057. https://doi.org/10.1056/NEJMoa1414266. It presents the global picture of diabetes for different types of diabetes and populations and provides information on specific actions that can be taken, such as proven measures to prevent type 2 diabetes and best management of all forms of diabetes to avoid subsequent complications. Bethesda, MD 20894, Web Policies Incorporating uncertainty measurement in the International Diabetes Federation Diabetes Atlas methodology for estimating global and national prevalence of diabetes in adults [O] . In the post-trial ACCORDION Study, prior intensive glycaemic control during the ACCORD study was associated with a sustained 58% risk reduction in progression diabetic retinopathy compared with standard therapy despite similar HbA1c levels in the post-trial period [39]. Lee-Ling Lim reported receiving grants and/or honoraria for consultancy or giving lectures from Abbott, AstraZeneca, Boehringer Ingelheim, Merck Sharp & Dohme, Novo Nordisk, Pfizer, Procter & Gamble Health, Roche, Sanofi, Servier and Zuellig Pharma. Despite the availability of new treatment classes, glycaemic control in patients with diabetes remained suboptimal globally [5]. Cardiovascular risk reduction with liraglutide: an exploratory mediation analysis of the LEADER trial. Lancet. Teo ZL, Tham YC, Yu M, Cheng CY, Wong TY, Sabanayagam C. Eye (Lond). J Am Heart Assoc. Google Scholar. Wang H1, Li N1, Chivese T2, Werfalli M3, Sun H4, Yuen L5, Hoegfeldt CA6, Elise Powe C7, Immanuel J5, Karuranga S4, Divakar H8, Levitt N9, Li C1, Simmons D6, Yang X1, Introduction. The incidence of myocardial infarction in white, South Asian, and Afro-Caribbean patients with type2 diabetes (U.K. Given that the majority of patients with diabetes have not yet developed cardiorenal events and on the basis of consistent evidence from randomized clinical trials (RCTs) and epidemiological analysis, notably that from UKPDS [4, 20, 26, 32, 37], ADVANCE [23, 25, 27], and VERIFY [33,34,35], glycaemic control should be achieved early and safely with treatment goals close to near normal value. EClinicalMedicine. Highly Influential Citations. UKPDS 88: Historical HbA1c might explain legacy effect [37]. Research studies suggest that diabetes is a risk factor for severe COVID-19-related disease, resulting in a greater . Before The opinions expressed in the manuscript are those of the authors. The total number of people living with diabetes is projected to rise to 643 million by 2030 and 783 million by 204 5. Front Endocrinol (Lausanne). Diabetes Care. Rossing P, Caramori ML, Chan JCN, et al. Besides, to ensure accessibility, affordability, and sustainability of healthcare provision, a pragmatic approach is needed to optimize the use of all available drugs, including new and old, to reduce the burden of diabetes and its complications. NCI CPTC Antibody Characterization Program. 5. PubMed Central Interactive effect of prepregnancy overweight/obesity and GDM history on prevalence of GDM in biparous women. 2021;44(5):123641. A global perspective. https://doi.org/10.2337/dc19-2251. Diabet Med. Causal Associations of PM2.5 and GDM: A Two-Sample Mendelian Randomization Study. Epidemiology of type2 diabetesglobal burden of disease and forecasted trends. Diabetes Obes Metab. View the Diabetes Atlas 2022 Reports, 1 in 10 adults are living with diabetes. 1, 2 Recent global estimates indicate that 537 million adults have diabetes, of whom 80% live in low-income and middle-income countries (LMICs). Khunti K, Bellary S, Karamat MA, et al. First published in 2000, the IDF Diabetes Atlas is produced by IDF in collaboration with a committee of scientific experts from around the world. IDF Diabetes Atlas 2021; IDF Guide for Epidemiology Studies; Atlas presentation; IDF Diabetes Atlas 2022 Reports; . Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type2 diabetes (J-DOIT3): an open-label, randomised controlled trial. https://doi.org/10.2337/dc17-1144. 2023 Feb 23:2023.02.16.23286014. doi: 10.1101/2023.02.16.23286014. 6) [59]. CI confidence interval, HbA1c glycated haemoglobin, OGLD oral glucose-lowering drugs, OR odds ratio, SD standard deviation, SUs sulfonylureas, T2D type2 diabetes. IDF Diabetes Atlas Committee presents 10th edition under the title " IDF Diabetes Atlas-10th Edition ". Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9. Chan JCN, Lim LL, Wareham NJ, et al. In this 5-year study, the intervention group achieved a more durable attainment of HbA1c<7.0% with lower risk of glycaemic deterioration (HbA1c7.0% at two consecutive scheduled visits, 3months apart) and treatment escalation including insulin than patients treated with initial metformin monotherapy (HR 0.51; 95%CI 0.45, 0.58; p<0.0001). 2020;10(1):10711. 13. Lachin JM, Bebu I, Nathan DM, DCCT/EDIC Research Group. Mol Metab. https://doi.org/10.1038/ki.2012.401. Kadowaki T, Yamamoto F, Taneda Y, et al. In the present review, we discuss the need to use a pragmatic, albeit evidence-based approach, to combine glucocentric and cardiorenal risk reduction strategies to improve the outcomes in patients with T2D, with particular relevance to Asia Pacific. https://doi.org/10.1016/S0140-6736(19)32131-2. Diabetes Metab J. Federal government websites often end in .gov or .mil. Epub 2021 Dec 6. Lean MEJ, Leslie WS, Barnes AC, et al. Hayward RA, Reaven PD, Wiitala WL, et al. Glycemic targets: Standards of medical care in diabetes-2022. Arch Gynecol Obstet. Kidney Int. The .gov means its official. Diabetologia. Global report on diabetes: executive summary. Avenue Herrmann-Debroux 54 Diabetes prevalence by age and sex in 2021: IDF Diabetes Atlas. government site. Ueki K, Sasako T, Okazaki Y, et al. For every 1% HbA1c level higher than these respective threshold values, there was a 38% higher risk for macrovascular events (vs a 7% threshold) and 40% higher risk for microvascular events and 38% higher risk for death (vs a 6.5% threshold; all p<0.0001) [25]. Diabetes Obes Metab. Einarson TR, Acs A, Ludwig C, Panton UH. In the 10-year post-trial period of VADT, patients with T2D assigned to intensive glycaemic control for 5.6years had a 17% lower risk of MACE than those assigned to standard therapy, although there was no significant effect on mortality [40]. Effects of anti-diabetes medications on cardiovascular and kidney outcomes in Asian patients with type2 diabetes: a rapid evidence assessment and narrative synthesis. Brussels,Belgium: International Diabetes Federation, 2021. International Diabetes Federation.IDF Diabetes Atlas, 10th edn. 2016;39(5):73842. The number of children and adolescents (i.e. The IDF practice guidelines recommended using the A-B-C-D approach for choosing second-line treatment after metformin, where A stands for age (young patients might benefit from lower HbA1c goals); B for bodyweight (overweight/obese patients might benefit from treatments with weight-neutral or weight-loss effects); C for complications (patients with CKD or CVD might benefit from treatments with organ-protective effects); and D for duration (patients with long disease duration are likely to have complications and required treatment adjustment, including the use of insulin) [15]. The figures for currently observed as well as projected global diabetes prevalence from the IDF (International Diabetes Federation) atlas are the standard sources when reporting the burden of diabetes. 10-year follow-up of intensive glucose control in type2 diabetes. eCollection 2023. Attenuated risk association of end-stage kidney disease with metformin in type2 diabetes with eGFR categories 14. Fixed effects meta-analysis was conducted to estimate standardized pooled prevalence of GDM by IDF regions and World Bank country income groups. Lim LL, Lau ESH, Ozaki R, et al. https://doi.org/10.1056/NEJMoa0802743. We have been publishing global estimates of the prevalence of diabetes for just over 20 years. Lee-Ling Lim. The proposed model using a 10-fold cross validation performed better in diabetes in precision, accuracy, recall and F1-score of 96.5%, 93.55%, 79.2% and 87.0%, respectively. https://doi.org/10.1371/journal.pmed.1003367. The International Diabetes Federation (IDF) is an umbrella organization of over 230 national diabetes associations in 170 countries and territories. Evolution of Type 2 Diabetes Management from a Glucocentric Approach to Cardio-Renal Risk Reduction: The New Paradigm of Care, Portuguese-Brazilian evidence-based guideline on the management of hyperglycemia in type 2 diabetes mellitus, Cardiovascular outcomes trials: a paradigm shift in the current management of type 2 diabetes, Inadequate Use of Newer Treatments and Glycemic Control by Cardiovascular Risk and Sociodemographic Groups in US Adults with Diabetes in the NIH Precision Medicine Initiative All of Us Research Program, Redefining diabetes mellitus treatments according to different mechanisms beyond hypoglycaemic effect, Glycemic Control and Prevention of Diabetic Complications in Low- and Middle-Income Countries: An Expert Opinion, 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. Background Citations. Among overweight patients treated with metformin, there was also persistent risk reduction for any diabetes-related endpoint (21%, p=0.01), myocardial infarction (33%, p=0.005), and death from any cause (27%, p=0.002) [32]. After a median follow-up of 8.5years, the primary composite outcome (myocardial infarction, stroke, revascularisation, or all-cause mortality) occurred in 109 patients in the intensive treatment group compared with 133 in the conventional treatment group with a non-significant HR of 0.81 (95%CI 0.63, 1.04; p=0.094) [30]. 2023 Feb 13;11(2):171. doi: 10.3390/toxics11020171. This number is predicted to rise to 643 million by 2030 and 783 million by 2045. Stratton IM, Adler AI, Neil HA, et al. 2021;20(1):189. https://doi.org/10.1186/s12933-021-01366-8. In the Japan Diabetes Optimal Treatment study for three major risk factors of CVD (J-DOIT3), researchers compared the effects of intensive versus conventional control of multiple risk factors in Japanese patients with T2D (including glycaemia, hypertension, and/or dyslipidaemia) on clinical outcomes [30]. In obese people with T2D diagnosed for less than 6years, weight loss of at least 15kg might lead to remission of diabetes for 2years [50]. Approximately 60% of patients were treated with SUs (n=32,558). International Diabetes Federation. In contrast, delaying this reduction in HbA1c until 10years after diagnosis showed seven times lower risk reduction of 2.7% (95%CI 3.1, 2.3). Subsequent meta-analyses including more studies confirmed that SGLT2 inhibitors reduced the risk of MACE by 10% (HR 0.90; 95%CI 0.85, 0.95) [47] and GLP-1 receptor agonists by 14% (HR 0.86, 95%CI 0.79, 0.94; p=0.006) [9]. Multifactorial intervention has a significant effect on diabetic kidney disease in patients with type2 diabetes. The International Diabetes Federation (IDF) has adopted a pragmatic approach by reviewing available guidelines and integrating the recommendations applicable to primary care settings around the world [15]. . The Vildagliptin Efficacy in combination with metfoRmIn For earlY treatment of T2D (VERIFY) study compared the effects of early dipeptidyl peptidase4 (DPP4) inhibitor (vildagliptin)metformin combination therapy versus standard metformin monotherapy on durable glycaemic control in patients with newly or recently diagnosed T2D with 18.6% of patients being of Asian descent [33]. Number of people living with diabetes remained suboptimal globally [ 5 ] Atlas 2021 20... By 2045 Federation.IDF diabetes Atlas, 10th edn adjusting the Use of Glucose-Lowering Agents in the Real-World Management! Jm, Bebu I, Nathan DM, DCCT/EDIC Research Group Caramori ML, Chan,... 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